New Approaches to Using Gabapentin in Psychiatry: Focus on Anxiety Disorders
Introduction: Why Reevaluate Gabapentin in Psychiatry Now? Gabapentin, a structural analog of gamma-aminobutyric acid (GABA), was originally developed as an anticonvulsant and remains widely used for neuropathic pain. However, over the past decade, growing interest has emerged around its psychiatric applications, particularly in treating anxiety disorders. While not FDA-approved for this purpose, gabapentin has shown […]
Gabapentin in the Treatment of Post-COVID-19 Neuropathic Pains
Introduction: Neuropathic Pain in Long COVID As the global health system continues to grapple with the long-term consequences of COVID-19, chronic neurological symptoms have emerged as a major challenge for patients and clinicians alike. Among these, neuropathic pain, including burning sensations, tingling, and electric shock-like discomfort, is increasingly recognized in individuals experiencing post-acute sequelae of […]
Gabapentin and Personalized Medicine: Genetic Factors and Optimization of Dosages
Introduction: Gabapentin Enters the Era of Personalized Medicine Gabapentin has long been prescribed for its anticonvulsant and analgesic properties, especially in the treatment of neuropathic pain, fibromyalgia, and chronic pelvic pain. Despite its widespread use, clinical response to gabapentin is highly variable, with some patients experiencing profound relief, and others reporting minimal benefit or intolerable […]
Gabapentin for Functional Dyspepsia: Neuroscience Meets the Stomach
Invisible Pain: Visceral Hypersensitivity as a Target Functional dyspepsia (FD) affects up to 10% of the global population, yet it remains frustratingly difficult to treat. Patients typically present with upper abdominal discomfort, early satiety, bloating, or epigastric pain without any visible structural abnormality on endoscopy. When acid suppression fails and there’s no gastroparesis or peptic […]